ABCG2 p.Gln126Lys

ClinVar: c.376C>T , p.Gln126* ? , association
Predicted by SNAP2: A: D (71%), C: D (66%), D: D (80%), E: D (75%), F: D (80%), G: D (80%), H: D (63%), I: D (75%), K: D (80%), L: D (80%), M: D (63%), N: D (75%), P: D (85%), R: D (85%), S: D (75%), T: D (75%), V: D (71%), W: D (85%), Y: D (75%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, R: D, S: D, T: D, V: D, W: D, Y: D,

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[hide] Ogura J, Kuwayama K, Sasaki S, Kaneko C, Koizumi T, Yabe K, Tsujimoto T, Takeno R, Takaya A, Kobayashi M, Yamaguchi H, Iseki K
Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.
Biochem Pharmacol. 2015 Sep 1;97(1):89-98. doi: 10.1016/j.bcp.2015.06.021. Epub 2015 Jun 25., [PMID:26119820] [PubMed]

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