ABCG2 p.Lys453Ala

Predicted by SNAP2: A: N (66%), C: D (59%), D: D (59%), E: N (53%), F: D (71%), G: N (53%), H: N (72%), I: N (57%), L: D (53%), M: N (57%), N: N (66%), P: D (59%), Q: N (72%), R: N (66%), S: N (61%), T: N (66%), V: N (66%), W: D (75%), Y: D (66%),
Predicted by PROVEAN: A: D, C: D, D: D, E: N, F: D, G: D, H: D, I: D, L: D, M: D, N: D, P: D, Q: N, R: N, S: D, T: D, V: D, W: D, Y: D,

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[hide] Szafraniec MJ, Szczygiel M, Urbanska K, Fiedor L
Determinants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).
Drug Metab Rev. 2014 Nov;46(4):459-74. doi: 10.3109/03602532.2014.942037. Epub 2014 Jul 18., [PMID:25036722] [PubMed]

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[hide] Haider AJ, Cox MH, Jones N, Goode AJ, Bridge KS, Wong K, Briggs D, Kerr ID
Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences.
Biosci Rep. 2015 Jul 17;35(4). pii: e00241. doi: 10.1042/BSR20150150., [PMID:26294421] [PubMed]

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