ABCG2 p.Lys452Ala

Predicted by SNAP2: A: D (80%), C: D (71%), D: D (91%), E: D (91%), F: D (85%), G: D (85%), H: D (71%), I: D (80%), L: D (80%), M: D (71%), N: D (80%), P: D (91%), Q: D (80%), R: N (82%), S: D (85%), T: D (85%), V: D (85%), W: D (85%), Y: D (91%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, L: D, M: D, N: D, P: D, Q: N, R: N, S: D, T: D, V: D, W: D, Y: D,

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[hide] Cai X, Bikadi Z, Ni Z, Lee EW, Wang H, Rosenberg MF, Mao Q
Role of basic residues within or near the predicted transmembrane helix 2 of the human breast cancer resistance protein in drug transport.
J Pharmacol Exp Ther. 2010 Jun;333(3):670-81. Epub 2010 Mar 4., [PMID:20203106] [PubMed]

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[hide] Honorat M, Falson P, Terreux R, Di Pietro A, Dumontet C, Payen L
Multidrug resistance ABC transporter structure predictions by homology modeling approaches.
Curr Drug Metab. 2011 Mar;12(3):268-77., [PMID:21470105] [PubMed]

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[hide] Szafraniec MJ, Szczygiel M, Urbanska K, Fiedor L
Determinants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).
Drug Metab Rev. 2014 Nov;46(4):459-74. doi: 10.3109/03602532.2014.942037. Epub 2014 Jul 18., [PMID:25036722] [PubMed]

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