ABCG2 p.Tyr605Cys

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PMID: 11807788 [PubMed] Kage K et al: "Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization."
No. Sentence Comment
151 to Ala and Tyr-605 to Cys), HABCRP-37 (Thr-82 to Ala) or HABCRP-74 (Ser-25 to Pro, Arg-309 to Gly and Ala-632 to Val), also expressed mutant BCRP protein, but cells transfected with HABCRP-86 (Lys-86 to Ile) did not express BCRP protein and therefore exhibited no drug resistance.
ABCG2 p.Tyr605Cys 11807788:151:11
status: VERIFIED
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